Improving the Quality of Life of Patients with Headache Treated with Neural Therapy

Autores/as

DOI:

https://doi.org/10.37467/gkarevmedica.v9.3015

Palabras clave:

Headache, Health-related quality of life, Local Anesthetics, Lidocaine, Procaine, Neural therapy, SF-36 scale

Resumen

Primary headaches (PHs) are common health complaints with a high impact on health-related quality of life (HRQOL). Treatment is multifactorial, including pharmacological and non-pharmacological strategies. Neural therapy (NT) is a regulatory treatment system that uses local anesthetic injections in chosen points to treat pain. This study aims to evaluate the effect of NT on the HRQOL of patients with PHs. Quasi-experimental prospective study involving 93 patients treated. The impact on HRQOL was evaluated through the SF-36 health, before and after treatment. Seven out of the eight items measured on the SF-36 scale improved after the intervention (p<0.001).

Citas

Abu, N., Tanprawate, S., Lambru, G., Torkamani, M., Jahanshahi, M., & Matharu, M. (2015). Quality of Life in Primary Headache Disorders: a Review. Cephalalgia, 36(1), 67-91.. doi:10.1177/0333102415580099

American College Of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Acute Headache, Edlow, J., Panagos, P., Godwin, S., Thomas, T., & Decker, W. (2008). Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department with Acute Headache. Annals of Emergency Medicine, 52(4). doi: 10.1016/j.annemergmed.2019.07.009

Aurora, S., Dodick, D., Diener, H., DeGryse, R., Turkel, C., Lipton, R., & Silberstein, S. (2014). Onabotulinumtoxina for Chronic Migraine: Efficacy, Safety, and Tolerability in Patients Who Received All Five Treatment Cycles in the PREEMPT Clinical Program. Acta Neurol Scand, 129, 61– 70.

Autret, A., Roux, S., Rimbaux-Lepage, S., Valade, D., Debiais, S. & West Migraine Study Group (2010). Psychopathology and Quality of Life Burden in Chronic Daily Headache: Influence of Migraine Symptoms. The Journal of Headache and Pain 11, 247–253. https://doi.org/10.1007/s10194-010-0208-1

Bahekar, A., Singh, S., Saha, S., Molnar, J., & Arora, R. (2007). The Prevalence and Incidence of Coronary Heart Disease is Significantly Increased in Periodontitis: a Meta-Analysis. American Heart Journal, 154(5), 830-7. doi:10.1016/j.ahj.2007.06.037

Baraff, L., Byyny, R., Probst, M., Salamon, N., Linetsky, M., & Mower, W. (2010). Prevalence of Herniation and Intracranial Shift on Cranial Tomography in Patients with Subarachnoid Hemorrhage and a Normal Neurologic Examination. Academic Emergency Medicine, 17(4). doi:10.1111/j.1553-2712.2010.00704.x

Barop, H. (1996). Lehrbuch und Atlas der Neuraltherapie nach Huneke. Hippokrates.

Becker, W., Findlay, T., Moga, C., Scott, N., Harstall, C., & Taenzer, P. (2015). Guideline for Primary Care Management of Headache in Adults. Canadian family physician Medecin de famille canadien, 61(8), 670–679.

Benz, T., Nüssle, A., Lehmann, S., Gantenbein, AR, Sándor, PS, Elfering, A., Aeschlimann, A. G., & Angst, F. (2017). Salud & Health and Quality of Life in Patients with Medication Overuse Headache Syndrome after Standardized Inpatient Rehabilitation. Medicine, 96 (47), e8493. https://doi.org/10.1097/MD.0000000000008493

Blumenfeld, A., Ashkenazi, A., Napchan, U., Bender, S., Klein, B., Berliner, R., Ailani, J., Schim, J., Friedman, D., Charleston, L., Young, W., Robertson, C., Dodick, D., Silberstein, S., & Robbins, M. (2013). Expert Consensus Recommendations for the Performance of Peripheral Nerve Blocks for Headaches a Narrative Review. Headache, 53(3), 437-46.

Burch, R., Rizzoli, P., & Loder, E. (2018). The Prevalence and Impact of Migraine and Severe Headache in the United States: Figures and Trends from Government Health Studies. Headache, 58(4), 496-505. doi:10.1111/head.13281

Buse, D., Loder, E., Gorman, J., Stewart, W., Reed, M., Fanning, K., Serrano, D., & Lipton, R (2013). Sex Differences in the Prevalence, Symptoms, and Associated Features of Migraine, Probable Migraine and Other Severe Headache: Results of the American Migraine Prevalence and Prevention (AMPP) Study. Headache, 53(8), 1278-99. doi:10.1111/head.12150

Cassuto, J., Sinclair, R., & Bonderovic, M. (2006). Anti-Inflammatory Properties of Local Anesthetics and their Present and Potential Clinical Implications. Acta Anaesthesiol Scand, 50(3), 265-82. doi:10.1111/j.1399-6576.2006.00936.x

Center of Disease Control and Prevention. (n.d). Health-Related Quality of Life (HRQOL). HRQOL Concepts. https://www.cdc.gov/hrqol/concept.htm

Chiang, C., Schwedt, T., Wang, S., & Dodick, D. (2014). Treatment of Medication-Overuse Headache: a Systematic Review. Cephalalgia, 36(4), 371-86. doi:10.1177/0333102415593088

Chowdhury, D. (2012). Tension type headache. Annals of Indian Academy of Neurology, 15(1), S83–S88. doi:10.4103/0972-2327.100023

Clinch, C. (2001). Evaluation of acute headaches in adults. American Family Physician, 63(4), 685-92.

Cornelissen, P., Van Kleef, M., Mekhail, N., Day, M., & Van Zundert, J. (2009). Persistent Idiopathic Facial Pain. Evidence-Based Interventional Pain Medicine According to Clinical Diagnoses. PAIN Practice, 9(6), 443–8. doi:10.1111/j.1533-2500.2009.00332.x

Diener, H., Holle, D., Dresler, T., & Gaul, C. (2018). Chronic Headache Due to Overuse of Analgesics and Anti-Migraine Agents. Dtsch Arztebl Int, 115(22), 365-370. doi:10.3238/arztebl.2018.0365

Diener, H., Matias, G., Hartung, E., Pfaffenrath, V., Ludin, H., & Nappi, G. D. (2002). Efficacy and Tolerability in Migraine Prophylaxis of Flunarizine in Reduced Doses: a Comparison with Propranolol 160 Mg Daily. Cephalalgia, 22(3), 209-21. doi:10.1046/j.1468-2982.2002.t01-1-00309.x

Do, T., Remmers, A., Schytz, H., Schankin, C., Obermann, M., Hansen, J., Sinclair, A., Gantenbein, A., & Schoonman, G. (2018). Red and Orange Flags for Secondary Headaches in Clinical Practice. American Academy of Neurology , 92(3), 1-11. doi:10.1212/WNL.0000000000006697

Dodick, D., Turkel, C., Degryse, R., Aurora, S., Silberstein, S., & Lipton, R. (2010). Onabotulinumtoxina for Treatment of Chronic Migraine: Pooled Results from the Double-Blind, Randomized, Placebo-Controlled Phases of the PREEMPT Clinical Program. Headache, 50, 921-36.

Egli, S., Pfister, M., Ludin, S., Puente de la Vega, K., Busato, A., & Fischer, L. (2015). Long-Term Results of Therapeutic Local Anesthesia (Neural Therapy) in 280 Referred Refractory Chronic Pain Patients. BMC complementary and alternative medicine, 15. doi:10.1186/s12906-015-0735-z

Fischer, L. (2001). Neuraltherapie nach Huneke. Grundlagen, Technik, praktische Anwendung. 2nd. Hippokrates.

Fokunang, C., Fokunang, E., Frederick, K., Ngameni, B., & Ngadjui, B. (2017). Overview of Non-Steroidal Anti-Inflammatory Drugs (Nsaids) in Resource Limited Countries. doi:10.15406/mojt.2018.04.00081

Frank, B. (1999). Neural therapy. Physical Medicine and Rehabilitation Clinics of North America, 10(3), 573-82.

Guitera, V., Muñoz, P., Castillo, J., & Pascual, J. (2002). Quality of Life in Chronic Daily Headache A Study in a General Population. Neurology, 58 (7) 1062-1065. https://doi.org/10.1212/WNL.58.7.1062

Hahnenkamp, K., Durieux, M., Hahnenkamp, A., Schauerte, S., Hoenemann, C., Vegh, V., Theilmeier, G., & Hollmann, M (2006). Local Anaesthetics Inhibit Signalling of Human NMDA Receptors Recombinantly Expressed in Xenopus Laevis Oocytes: Role of Protein Kinase C. British Journal of Anaesthesia, 96(1), 77-87. doi:10.1093/bja/aei271

Hainer, B., & Matheson, E. (2013). Approach to Acute Headache in Adults. American Family Physician 87(10), 682-687.

Harirforoosh, S., Asghar, W., & Jamali, F. (2014). Adverse Effects of Nonsteroidal Antiinflammatory Drugs: An Update of Gastrointestinal, Cardiovascular and Renal Complications. Journal of Pharmacy & Pharmaceutical Sciences, 16(5), 821–847. doi:10.18433/J3VW2F

Headache Classification Committee of the International Headache Society (IHS). (2018). The International Classification of Headache Disorders, 38(1), 3rd, 1-211.

Hollmann, M., Herroeder, S., Kurz, K., Hoenemann, C., Struemper, D., Hahnenkamp, K., & Durieux, M. (2004). Time-dependent Inhibition of G Protein-coupled Receptor Signaling by Local Anesthetics. Anesthesiology, 100(4), 852-60. doi:10.1097/00000542-200404000-00015

Jackson, J., Kuriyama, A., Kuwatsuka, Y., Nickoloff, S., Storch, D., Jackson, W., Zhang, Z., & Hayashino, Y. (2019). Beta-blockers for the Prevention of Headache in Adults, a Systematic Review and Meta-Analysis. PLoS One, 14(3). doi:10.1371/journal.pone.0212785

Lai, K., Niddam, D., Fuh, J., Chen, S., Wang, Y., Chen, W., Wu, J., & Wang, S. (2017). Flunarizine versus Topiramate for Chronic Migraine Prophylaxis: a Randomized Trial. Acta Neurol Scand, 135(4), 476-483. doi:10.1111/ane.12626

Locker, T., Thompson, C., Rylance, J., & Mason, S. (2006). The Utility of Clinical Features in Patients Presenting with Nontraumatic Headache: an Investigation of Adult Patients Attending an Emergency Department. Headache, 46(6), 954–961 doi:10.1111/j.1526-4610.2006.00448.x

Lundqvist, C., Bjørn, R., Straand, J., & Kristoffersen, J. (2019). Severity of Analgesic Dependence and Medication-overuse Headache. Journal of Addiction Medicine, 13(5), 346–353.. doi:10.1097/ADM.0000000000000504

McCrae, J., Morrison, E., MacIntyre, I., Dear, J., & Webb, J. (2018). Long‐term Adverse Effects of Paracetamol – a Review. British Journal of Clinical Pharmacology, 84(10), 2218-2230. doi:10.1111/bcp.13656

Mermod, J., Fischer, L., Staub, L., & Busato, A. (2008). Patient Satisfaction of Primary Care for Musculoskeletal Diseases: a Comparison between Neural Therapy and Conventional Medicine. BMC Complement ary and Alternative Medicine, 8(33). doi: 10.1186/1472-6882-8-33

Mitsikostas, D., Ashina, M., Craven, A., Diener, H., Goadsby, P., Ferrari, M., Lampl, C., Paemeleire, K., Pascual, J., Siva, A., Olesen, J., Osipova, V., & Martelletti, P. (2015). European Headache Federation Consensus on Technical Investigation for Primary Headache Disorders. Journal of Headache and Pain, 17(5) doi:10.1186/s10194-016-0596-

Morillo, L., Alarcon, F., Aranaga, N., Aulet, S., Chapman, E., Conterno, L., Estevez, E., Garcia-Pedroza, F., Garrido, J., Macias-Islas, M., Monzillo, P., Nunez, L., Plasencia, N., Rodriguez, C., Takeuchi, Y., & Latin American Migraine Study Group. (2005). Prevalence of Migraine in Latin America. Headache, 45(2), 106-117 . doi:10.1111/j.1526-4610.2005.05024.x

Mulleners, W., McCrory, D., & Linde, M. (2015). Antiepileptics in Migraine Prophylaxis: an Updated Cochrane Review. Cephalalgia, 35(1), 51-62. doi:10.1177/0333102414534325

Muñoz-Ceron, J., Rueda-Sánchez, M., Pradilla-Vesga, O., Volcy, M., Hernández, N., Ramírez, S., Sobrino, F., Uribe, B., Guerra, C., Jiménez, J., Ramos, M., Pradilla, G., Martínez, J., Torres, C. y Torres, G. (2020). Guía de la Asociación Colombiana de Neurología para el tratamiento preventivo de la migraña crónica, cefalea tipo tensión crónica, hemicránea continua y cefalea diaria persistente de novo. Acta Neurológica Colombiana, 36(3), 131-149. doi:10.22379/24224022299

Olesen, J., Gustavsson, A., Svensson, M., Wittchen, H., & Jönsson, B. (2012). Study group; European Brain Council. The Economic Cost of Brain Disorders in Europe. European Journal of Neurology, 19(1), 155-162. doi:10.1111/j.1468-1331.2011.03590.x

Organization, World Health. (1994). Quality of Life Assessment. An annotated bibliography. https://apps.who.int/iris/bitstream/handle/10665/61629/WHO_MNH_PSF_94.1.pdf?sequence=1&isAllowed=y

Ozyalcin, S., Talu, G., Kiziltan, E., Yucel, B., Ertas, M., & DiscI, R. (2005). The Efficacy and Safety of Venlafaxine in the Prophylaxis of Migraine. Headache, 45, 144–152.

Pradilla, G., Léon, FE, Vesga, B. y Grupo, G. (2003). Estudio Neuroepidemiológico Nacional (Epineuro) Colombiano. Revista Panamericana Salud Pública, 14(2), 104-111. https://www.scielosp.org/pdf/rpsp/2003.v14n2/104-111/es

Rey, M., Muñoz, M., Catalán, M., & Vinyes, D. (2021). Treatment of Localized Vulvar Pain with Neural Therapy: A Case Series and Literature Review. Complement Med Res, 1-7.

Sabatke, S., Scola, R., Paiva, E., & Kowacs, P. (2015). Injecction of Trigger Points in the Temporal Muscles of Patients with Miofascial Syndrome. Arquivos de Neuropsiquiatria, 73(10), 861–6. www.ncbi.nlm.nih.gov/pubmed/26465403

Scholz, A. (2002). Mechanisms of (Local) Anaesthetics on Voltage-gated Sodium and Other Ion Channels. British Journal of Anaesthesia, 89(1), 52-61. doi:10.1093/bja/aef163

Silberstein, S. (2017). Topiramate in Migraine Prevention: A 2016 Perspective. Headache, 57(1), 165-178. doi:10.1111/head.12997

Strain, J., Strife, J., Kushner, D., Babcock, D., Cohen, H., Gelfand, M., Hernandez, R., McAlister, W., Parker, B., Royal, S., Slovis, T., Smith, W., & Rothner, A. (2000). Headache. American College of Radiology. ACR Appropriateness Criteria. Radiology, 215 Suppl, 855-860.

Sugimoto, M., Uchida, I., & Mashimo, T. (2003). Local Anaesthetics have Different Mechanisms and Sites of Action at the Recombinant N-methyl-D-aspartate (NMDA) Receptors. British Journal of Pharmacology, 138(5), 876-82. doi:10.1038/sj.bjp.0705107.

Tamburin, S., Lacerenza, M., Castelnuovo, G., Agostini, M., Paolucci, S., Bartolo, M., Bonazza, S., Federico, A., Formaglio, F., Giusti, E., Manzoni, G., Mezzarobba, S., Pietrabissa, G., Polli, A., Turolla, A., & Sandrini, G. (2016). Pharmacological and Non-pharmacological Spain in Neurorehabilitation. Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN). European Journal of Physiscal Rehabilitation Medicine, 52(5), 741-752.

Tittarelli R, P. M., Scarpellini, M., Marinelli, E., Bruti, V., Di Luca, N., Busardò, F., & Zaami, S. (2017). Hepatotoxicity of Paracetamol and Related Fatalities. European Review for Medical and Pharmacological Sciences, 95-101.

Tracey, K. (2002). The Inflammatory Reflex. Nature, 420, 853-9. doi:10.1038/nature01321

Vos, T., Flaxman, A. D., Naghavi, M., Lozano, R, Michaud, C., Ezzati, M., Shibuya, K., Salomon, J. A., Abdalla, S., Aboyans, V., Abraham, J., Ackerman, I., Aggarwal, R., Ahn, S. Y., Ali, M. K., Alvarado, M., Anderson, H. R., Anderson, L. M., Andrews, K. G., Atkinson, C., ... Memish, Z.A. (2012). Years Lived with Disability (YLDs) for 1160 Sequelae of 289 Diseases and Injuries 1990-2010: a Systematic Analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859), 2163-96. doi:10.1016/S0140-6736(12)61729-2

Wang, S. J., Fuh, J. L., Lu, S. R., & Juang., K. D. (2001). Quality of Life Differs among Headache Diagnoses: Analysis of SF-36 Survey in 901 Headache Patients. Pain, 89(2-3), 285–292. https://doi.org/10.1016/s0304-3959(00)00380-8

Weinschenk, S. (2012). Neural therapy—A review of the therapeutic use of local anesthetics. Acupuncture and Related Therapies 1, 5–9. doi:10.1016/j.arthe.2012.12.004.

Weinschenk, S., Brocker, J., Hotz, L., Strowitzki, T., & Joos, S. (2013). Successful Therapy of Vulvodynia with Local. Heidelberg University Neural Therapy Education an Research, 20, 1-7. doi:10.1159/000350023

Whyte, C., & Tepper, S. (2009). Adverse Effects of Medications Commonly Used in the Treatment of Migraine. Expert Review Neurotherapeutics, 9(9), 1379-1391.

Wongrakpanich, S., Wongrakpanich, A., Melhado, K., & Rangaswami, J. (2018). A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly. Aging Dis, 9(1), 143-150. doi:10.14336/AD.2017.0306

Xu, X., Liu, Y., Dong, M., Zou, D., & Wei, Y. (2017). Tricyclic Antidepressants for Preventing Migraine in Adults. Medicine, 96(10). doi:10.1097/MD.0000000000006989

Young, W.B., Ailani, J., Buse, D.C., Horblyuk, R., Hirman, J., Cady, R. (2020). Correlation Analysis of the Change in SF-36 with Change in Patient-Identified Most Bothersome Symptom and Monthly Migraine Days (MMDs) in Patients with Chronic Migraine (CM): Results of the PROMISE-2 Study (519). Neurology, 94(15), 519. doi:10.1016/j.jval.2020.04.993

Yu, S., & Han, X. (2015). Update of Chronic Tension-type Headache. Current Pain and Headache Reports, 19(1), 469. doi:10.1007/s11916-014-0469-5

Descargas

Publicado

2021-10-25

Cómo citar

Nassar Tobón, A. C., Geney Montes, M. C., Martínez Pacheco, F. H., Muñoz-Sellart, M., & Vinyes, D. (2021). Improving the Quality of Life of Patients with Headache Treated with Neural Therapy. MEDICA REVIEW. International Medical Humanities Review Revista Internacional De Humanidades Médicas, 9(1), 13–28. https://doi.org/10.37467/gkarevmedica.v9.3015

Número

Sección

Artículos de investigación